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Industry Profile: Biotechnology
Watch
for other profiles as we post them.
MAED
co-sponsored Massachusetts Works
for Life Sciences held on June
13, 2002.
"We need access to talent, which includes college
graduates, post-doctoral students, and university faculty. Frankly, when we
had to decide where to go, it took us probably a millisecond to say
Boston."
-- Gordon Binder, Chairman and CEO, Amgen. (The Boston
Globe, 11/11/99)
Scientific Leadership
-
Produced half of all Nobel Prize winners in the country.
-
Massachusetts is responsible for an estimated one-third of the world's biotechnology
-
World-class institutes of higher education, research universities, medical
schools and teaching hospitals.
-
Leading biotech pioneers including
Amgen,
Biogen,
Abbott
Labs,
Genzyme,
Millennium Pharmaceuticals,
Pfizer, and
Sepracor.
Technical and Research Talent
-
Consistently ranks #1 in the US for science and engineering graduate
students. (AeACyberstates 2002 Report)
-
The most highly educated workforce in the nation - ranked #1 in the US for
college attainment. (2000 U.S. Census Report)
-
Among the top states in overall university R&D. (AeACyberstates 2002 Report)
-
Deep-rooted culture of scientific research and innovation.
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Employment in the biotech research sectors grew 59% from 1997 to 1999. (2000 Massachusetts Biotechnology Council)
Rich Resources for Research Funding and Venture Capital
-
Highest per capita federally funded R&D expenditures in the nation. (AeACyberstates 2002 Report)
-
#1 in the US in per capita Small Business Innovation Research awards to
businesses, with almost 4 times as many SBIR grants per capita as California. (2000 SBIR)
-
#1 per capita in National Institute for Health research grants over $1.7
billion in 2001. (2001 NIH)
-
#1 in per capita venture capital investments. (2000 PWC/Venture Economics Survey)
Business and Partnership Infrastructure
-
Abundance of innovative startup companies over 7% of all establishments
and over 16% of all US employment in biotech and medical research are located
in Massachusetts. (2001 Index of the Massachusetts Innovation Economy)
-
Over 300 research, manufacturing and wholesale establishments in the drug
manufacturing industry employing more than 25,000 in Massachusetts. (2002, BLS)
-
Established industry support from organizations like the
Massachusetts
Biotechnology Council
and
Massachusetts Biomedical Initiative.
-
Opportunities in university research and business partnerships, technology
transfers, and commercialization and licensing opportunities.
Turning Innovations into Breakthrough Products
-
#1 in patent generation per capita. (2001 Index of the Massachusetts Innovation Economy)
-
New technology licenses issued by major nonprofit universities, hospitals
and research institutions increased by 28% between 1995-97 compared to 23%
nationwide. (2001 Index of the Massachusetts Innovation Economy)
-
Consistently top-ranked for FDA approval of investigational device
exemptions (IDEs) tripling from 1995 to 1998. (2000 MassMEDIC)
Accelerated Research and Product Time-to-Market
-
High density of professional services firms specializing in biotech, ranging
from law to architectural services, which are ready to facilitate commercial
application of R&D.
-
Innovations in bio-informatics with products from companies like
Spotfire
and
Rosetta Inpharmatics.
-
Leading area for IT, business communications and computer software
industries critical for information-intensive research.
Making Biotech History: Pivotal moments in Human Genome Research
First therapeutic application of a laser on humans.
Maxam-Gilbert method for rapid DNA sequencing developed at Harvard.
First patent for a genetically altered animal awarded to Harvard molecular
geneticists.
The MSH2 gene needed for DNA base mismatch repair detected at Dana Farber
Cancer Institute.
Development of the tissue engineering field by a doctor at Boston Children's
Hospital and a chemical engineer at MIT.
The first biotech-derived drugs for cancer treatment developed by
Biogen.
First genetically engineered blood clotting factor approved in the U.S.
developed by
Genetics Institute.
Continuous Innovation: Human Genome Research
-
The Whitehead Institute/MIT Center for Genome Research is an International
Human Genome Project Major Sequencing Site
Other research sites and projects include Genome Therapeutics, Harvard,
Boston University, Tufts, and Massachusetts General Hospital
Business Presence and Leadership
There are over 250 biotechnology companies in Massachusetts, from mature
industry leaders to entrepreneurial start-ups.
Biggest
Biotechnology Companies
[Ranked by
Mass. employees]
-
Genzyme
General
-
Wyeth/Genetics
Institute
-
Millipore
Corp
-
Biogen Inc.
-
Millennium Pharmaceuticals Inc.
-
AstraZeneca
Pharmaceuticals LP
-
Parexel
International Corporation
-
Serono
Inc.
-
Abt
Associates Clinical Trials
-
Alkermes
Inc.
[Source:
The Boston Business Journal,
Feb 2002]
Organizational Resources:
Massachusetts Biotechnology Council
(MBC)
Founded in 1985, the MBC is a private not for profit trade association
representing biotechnology companies in Massachusetts.
Massachusetts Biomedical Initiatives
(MBI)
MBI is a catalyst for economic development and job creation for the
biotechnology and medical device industries in Central Massachusetts.
Mass
means business
This site features information regarding incentives, real estate resources,
educational programs, research institutions, etc.,
brought to you by the Massachusetts
Department of Economic Development.
Recent Developments:
- Repligen
Corporation has received FDA
approval to market SecreFlo, a
synthetic version of the secretin
hormone, used for pancreatic
assessment.
- Ariad
Pharmaceuticals, Inc. recently
demonstrated potent tumor shrinkage
through metabolic cancer-cell
starvation.
- Syntonix
Pharmaceuticals, Inc. has raised
$35.8 million in a Series B
preferred stock financing that will
be used to put products into a
formal pre-clinical track and Phase
I trials.
- Genzyme
Transgenics Corporation received
$1.2 million from Fresenius AG, in
order for the latter to gain
additional rights to market
recombinant human serum albumin in
Japan.
- Biogen,
Inc. and the Massachusetts
Institute of Technology Biological
Engineering Division have
established a fellowship program to
train scientists in the biotech
industry, especially in toxicology.
[Source: Bioline, Massachusetts Biotechnology Council,
Summer 2002]
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